PICKYOUTH Technology

Technology

Protected Delivery-Protects actives from the gut environment

Liposomal encapsulation physically isolates both hydrophobic and hydrophilic actives, reducing degradation in gastric conditions and improving the fraction of intact compound that reaches the small intestine. For many nutrients (e.g., vitamin C, curcuminoids) liposomal formulations show significantly higher Cmax and AUC vs non-encapsulated forms.

Protected Delivery-Protects actives from the gut environment
Image
Image

Technology

Food-Grade & Scalable-Designed for industrial scale, food safety and consumer use

Converting lab liposomes to shelf-stable consumer products requires freeze-drying (lyophilization), spray-drying, or powder conversion with protective excipients. Our tech stack covers the full transition: bench formulation → pilot scale → validated production lines with stability protocols and third-party testing.

Technology
Technology

Technology

Next-Gen Engineering-Surface engineering & co-encapsulation

Surface modification reduces premature clearance and can target interactions with specific gut zones; co-encapsulation enables simultaneous delivery of complementary compounds (e.g., polyphenol + phospholipid carrier), improving pharmacokinetics and functional synergy. We evaluate PEGylation alternatives, polysaccharide shells, and solid-lipid hybrid approaches depending on the active.

Technology
Technology

Technology

Enhanced Bioavailability-Clinically improved absorption profiles

Meta-analyses and randomized crossover trials have demonstrated measurable increases in plasma exposure for liposomal vitamin C and other encapsulated nutrients, often showing 1.5–2× or greater bioavailability depending on formulation and active. We optimize particle size, zeta potential and encapsulation efficiency to reproduce these gains consistently.

Technology
Technology

PICKYOUTH Lab

PICKYOUTH Lab translates liposomal science into marketable products
From proof-of-concept and preclinical simulation to pilot scale manufacturing, our in-house lab controls formulation, analytics and stability to deliver safe, effective liposomal supplements.
Image
Image
LAB SOP

Our R&D workflow follows a structured path:

Our R&D workflow follows a structured path:

Target active → preformulation mapping → liposome prototype → analytical verification (size, EE, release) → stability & GI simulation → pilot scale manufacturing → third-party verification. We maintain a full documentation trail and COA archives for every batch.

Target active →
preformulation mapping →
liposome prototype → analytic verification (size, EE, release) → stability & GI simulation → pilot scale manufacturing → third-party verification. We maintain a full documentation trail and COA archives for every batch.

Image
Image

Capabilities:
1.Liposome formulation & optimization (phospholipid selection, particle engineering).
2.Encapsulation efficiency & release profiling (HPLC, UPLC).
3.Particle analytics: DLS, zeta-potential, particle size distribution, cryo-TEM
4.Solid-lipid & lyophilization conversion (freeze-dry and powder technologies for shelf stability).


5.Co-encapsulation & combination platform (hydrophilic + lipophilic payloads).
6.Stability & accelerated shelf-life testing; moisture barrier packaging development.
7.GMP vendor network & scale-up partners for contract manufacturing.

Capabilities:
1.Liposome formulation & optimization (phospholipid selection, particle engineering).
2.Encapsulation efficiency & release profiling (HPLC, UPLC).
3.Particle analytics: DLS, zeta-potential, particle size distribution, cryo-TEM
4.Solid-lipid & lyophilization conversion (freeze-dry and powder technologies for shelf stability).
5.Co-encapsulation & combination platform (hydrophilic + lipophilic payloads).
6.Stability & accelerated shelf-life testing; moisture barrier packaging development.
7.GMP vendor network & scale-up partners for contract manufacturing.

Image
Image

Professional Nutritional Scientists

Custom Section 10 Image
Prof. Patrick Martinez
Head of Lipid Formulation

20 years in lipid-based delivery systems. Led formulation teams for oral nanocarrier projects; expertise in phospholipid selection, encapsulation efficiency, and scale-up. Published on liposomal stability and lyophilization techniques

Custom Section 10 Image
Dr. Sarah Parker
Analytical & Process Lead

MSc in Analytical Chemistry; specialist in DLS, cryo-TEM, release kinetics, and HPLC quantitation. Responsible for analytical method development and GMP transfer.

Custom Section 10 Image
Dr. James Wilson
Biophysics & Surface Engineering

focuses on surface-modified liposomes and polysaccharide coatings for enhanced GI resilience and targeting. Co-authored reviews on surface modification strategies.

Custom Section 10 Image
Dr. Thomas Brown
Nutritional Science & Clinical Translation

designs human bioavailability studies, PK analysis and clinical endpoints for liposomal formulations. Experience running randomized crossover absorption trials.