
— Science That Delivers Nutrition to the Cell
Advanced food-grade liposomal encapsulation protects actives from digestion, boosts absorption and stability, and enables targeted cellular delivery for superior bioavailability.
PICKYOUTH Technology
Technology
Protected Delivery-Protects actives from the gut environment
Liposomal encapsulation physically isolates both hydrophobic and hydrophilic actives, reducing degradation in gastric conditions and improving the fraction of intact compound that reaches the small intestine. For many nutrients (e.g., vitamin C, curcuminoids) liposomal formulations show significantly higher Cmax and AUC vs non-encapsulated forms.
Technology
Food-Grade & Scalable-Designed for industrial scale, food safety and consumer use
Converting lab liposomes to shelf-stable consumer products requires freeze-drying (lyophilization), spray-drying, or powder conversion with protective excipients. Our tech stack covers the full transition: bench formulation → pilot scale → validated production lines with stability protocols and third-party testing.
Technology
Next-Gen Engineering-Surface engineering & co-encapsulation
Surface modification reduces premature clearance and can target interactions with specific gut zones; co-encapsulation enables simultaneous delivery of complementary compounds (e.g., polyphenol + phospholipid carrier), improving pharmacokinetics and functional synergy. We evaluate PEGylation alternatives, polysaccharide shells, and solid-lipid hybrid approaches depending on the active.
Technology
Enhanced Bioavailability-Clinically improved absorption profiles
Meta-analyses and randomized crossover trials have demonstrated measurable increases in plasma exposure for liposomal vitamin C and other encapsulated nutrients, often showing 1.5–2× or greater bioavailability depending on formulation and active. We optimize particle size, zeta potential and encapsulation efficiency to reproduce these gains consistently.
PICKYOUTH Lab
Our R&D workflow follows a structured path:
Our R&D workflow follows a structured path:
Target active → preformulation mapping → liposome prototype → analytical verification (size, EE, release) → stability & GI simulation → pilot scale manufacturing → third-party verification. We maintain a full documentation trail and COA archives for every batch.
Target active →
preformulation mapping →
liposome prototype → analytic verification (size, EE, release) → stability & GI simulation → pilot scale manufacturing → third-party verification. We maintain a full documentation trail and COA archives for every batch.
Capabilities:
1.Liposome formulation & optimization (phospholipid selection, particle engineering).
2.Encapsulation efficiency & release profiling (HPLC, UPLC).
3.Particle analytics: DLS, zeta-potential, particle size distribution, cryo-TEM
4.Solid-lipid & lyophilization conversion (freeze-dry and powder technologies for shelf stability).
5.Co-encapsulation & combination platform (hydrophilic + lipophilic payloads).
6.Stability & accelerated shelf-life testing; moisture barrier packaging development.
7.GMP vendor network & scale-up partners for contract manufacturing.
Capabilities:
1.Liposome formulation & optimization (phospholipid selection, particle engineering).
2.Encapsulation efficiency & release profiling (HPLC, UPLC).
3.Particle analytics: DLS, zeta-potential, particle size distribution, cryo-TEM
4.Solid-lipid & lyophilization conversion (freeze-dry and powder technologies for shelf stability).
5.Co-encapsulation & combination platform (hydrophilic + lipophilic payloads).
6.Stability & accelerated shelf-life testing; moisture barrier packaging development.
7.GMP vendor network & scale-up partners for contract manufacturing.
Professional Nutritional Scientists
20 years in lipid-based delivery systems. Led formulation teams for oral nanocarrier projects; expertise in phospholipid selection, encapsulation efficiency, and scale-up. Published on liposomal stability and lyophilization techniques
MSc in Analytical Chemistry; specialist in DLS, cryo-TEM, release kinetics, and HPLC quantitation. Responsible for analytical method development and GMP transfer.
focuses on surface-modified liposomes and polysaccharide coatings for enhanced GI resilience and targeting. Co-authored reviews on surface modification strategies.
designs human bioavailability studies, PK analysis and clinical endpoints for liposomal formulations. Experience running randomized crossover absorption trials.